一、基本信息

姓　　名：孙博兴

职　　称：教授，博士生导师

所在部门：动物科学系

研究方向：生猪遗传育种与产业化研究

办公电话：0431-87836551

电子邮箱：sbx@jlu.edu.cn

二、教育与工作经历

教育经历

1993-1997年 解放军农牧大学 动物科学专业本科 学士

1997-2000年 解放军农牧大学 动物遗传育种专业研究生 硕士

2002-2005年 解放军军需大学 304am永利集团 生物化学与分子生物学研究生 博士

工作经历

2000.07-2008.08 解放军军需大学 304am永利集团 助教、讲师

2008.09-2016.08 304am永利集团 副教授

2011.09-2012.12 IOWA State University 访问学者

2016.09-至今 304am永利集团 教授

2016.12-2020.12 304am永利集团 304am永利集团副院长

2020.12-至今 304am永利集团 304am永利集团院长

三、主要教学科研工作

教学工作：在304am永利集团从事动物科学及相关专业教学、科研和技术推广工作，主讲本科生《动物育种学》、《猪生产学》及教学实习等课程，研究生《动物遗传原理与育种方法》、《动物遗传育种专论》、《现代动物生产专论》课程。

科研方向：生猪遗传育种和产业化研究

主持或参加科研项目二十多项，主持完成国家级星火计划重点项目1项、吉林省良种培育项目2项、吉林省发改委重点项目1项，参加国家科技支撑计划2项，主持或参加省部级项目科研4项。多年来致力于军牧1号白猪和东辽黑猪的选育研究，努力探索特色猪种开发新模式。在国内率先建立猪饲料效率分化资源群体，选育出料重比2.4:1的节粮型军牧1号白猪；选育肌内脂肪4.63%的优质型东辽黑猪，打造“猪领鲜”和“猪锦记”品牌，实现全产业链发展。发表中英文章60余篇，编著《图说高效养猪关键技术》(金盾出版社，8.0万字/11.1万字)，主编《动物遗传育种与繁殖实验指导》(304am永利集团出版社)9.3万字，主编《规模养猪技术》，副主编《猪生产学》（全国高等农林院校十三五、十四五规划教材），参编《现代畜牧业案例分析》（全国高等农林院校十三五规划教材），《畜牧兽医专业英语听力教程》（复旦大学出版社）。完成吉林省教学改革项目2项，304am永利集团教学改革项目1项，获304am永利集团教学改革成果二等奖1项，主持吉林省自然科学学术成果二等奖1项，吉林省登记科技成果2项。2011~2012年，在美国IOWA州立大学Jack Dekkers教授实验室做访问学者。主要开展生猪饲料效率、睾丸发育、产仔数等方面全基因组选择和功能基因组学研究。

学术兼职：吉林省畜牧兽医学会副理事长；中国畜牧兽医学会动物遗传育种学分会理事；动物遗传标记分会理事；东北养猪研究会常务理事；吉林省生猪遗传改良计划专家组成员。

研究生培养：已毕业研究生22人（赵伟、李传民、蔡飞翔、张晓军、潘韵致、周梦娇、刘鑫、郭佳、梁梦迪、齐佳佳、王振博、刘莹、刘鹏磊、程雨、王春旭、李靖、张绍萱、杨婷婷、杨素梅、王艳秋、魏华凯、罗柯），现有在读硕士研究生4人，博士3人，博士后2人。

四、获奖情况

2020年，吉林省科学技术奖二等奖，吉林特色猪种优良经济性状基因挖掘与功能解析（1/8）。

五、代表性论文与著作

1. Yan-Qiu Wang, He-Xuan Qu, Yan-Wei Dong, Jia-Jia Qi, Hua-Kai Wei, Hao Sun, Hao Jiang, Jia-Bao Zhang, Bo-Xing Sun, Shuang Liang. Inhibition of FSP1 impairs early embryo developmental competence in pigs. Theriogenology.. 2024 Jan 15:214:257-265. doi: 10.1016/j.theriogenology.2023.10.025. Epub 2023 Oct 26.

2. Hao Sun1, Yu Cheng , Yu He, Chao Cheng, Hongxia Zhao, Sumei Yang, Meng Wei, Jingxiu Yang, Shuang Liang, Chunyan Bai, Boxing Sun. Genome-wide association studies for the number of piglets born alive and dead in Dongliao black pigs. Anim Genet. 2024 Apr;55(2):282-285. doi: 10.1111/age.13385. Epub 2023 Dec 26.

3. Shao-Xuan Zhang, Da-Li Wang , Jia-Jia Qi , Yu-Wei Yang, Hao Sun, Bo-Xing Sun, Shuang Liang，Chlorogenic acid ameliorates the heat stress-induced impairment of porcine Sertoli cells by suppressing oxidative stress and apoptosis ，Theriogenology， 2023 Oct 19:214:148-156. doi: 10.1016/j.theriogenology.2023.10.018. Online ahead of print.

4. Ting-Ting Yang, Jia-Jia Qi, Bo-Xing Sun, He-Xuan Qu, Hua-Kai Wei1, Hao Sun, Hao Jiang, Jia-Bao Zhang, Shuang Liang，Maslinic Acid Supplementation during the In Vitro Culture Period Ameliorates Early Embryonic Development of Porcine Embryos by Regulating Oxidative Stress， Animals (Basel). 2023 Mar 13;13(6):1041. doi: 10.3390/ani13061041.

5. Hao Sun, Meng Wei, Zhong Xu, Chunyan Bai, Boxing Sun. PC-DOT: Improving genomic prediction ability of principal component regression by DOT product. Anim Genet. 2022 Dec;53(6):888-891. doi: 10.1111/age.13255. Epub 2022 Sep 27.

6. Zhang S, Sun B, Wang D, Liu Y, Li J, Qi J, Zhang Y, Bai C, Liang S. Chlorogenic Acid Ameliorates Damage Induced by Fluorene-9-Bisphenol in Porcine Sertoli Cells. Front Pharmacol. 2021 Jun 9;12:678772. doi: 10.3389/fphar.2021.678772. eCollection 2021.

7. Hu W, Zhang Y, Wang D, Yang T, Qi J, Zhang Y, Jiang H, Zhang J, Sun B, Liang S. Iron Overload-Induced Ferroptosis Impairs Porcine Oocyte Maturation and Subsequent Embryonic Developmental Competence in vitro. Front Cell Dev Biol. 2021 May 28;9:673291. doi: 10.3389/fcell.2021.673291. eCollection 2021.

8. Liu Y, Sun B, Zhang S, Li J, Qi J, Bai C, Zhang J, Liang S. Glycine alleviates fluoride-induced oxidative stress, apoptosis and senescence in a porcine testicular Sertoli cell line. Reprod Domest Anim. 2021 Jun;56(6):884-896. doi: 10.1111/rda.13930. Epub 2021 Mar 25.

9. Li J, Sun BX, Wang DL, Liu Y, Qi JJ, Nie XW, Bai CY, Zhang JB, Liang S. Melatonin ameliorates cypermethrin-induced impairments by regulating oxidative stress, DNA damage and apoptosis in porcine Sertoli cells. Theriogenology. 2021 Jun;167:67-76. doi: 10.1016/j.theriogenology.2021.03.011. Epub 2021 Mar 19.

10. Xiao Y, Yuan B, Hu W, Qi J, Jiang H, Sun B, Zhang J, Liang S. Tributyltin Oxide Exposure During in vitro Maturation Disrupts Oocyte Maturation and Subsequent Embryonic Developmental Competence in Pigs. Front Cell Dev Biol. 2021 Jun 28;9:683448. doi: 10.3389/fcell.2021.683448. eCollection 2021.

11. Qi JJ, Li XX, Zhang Y, Diao YF, Hu WY, Wang DL, Jiang H, Zhang JB, Sun BX, Liang S. Supplementation with asiatic acid during in vitro maturation improves porcine oocyte developmental competence by regulating oxidative stress. Theriogenology. 2021 Sep 15;172:169-177. doi: 10.1016/j.theriogenology.2021.06.013. Epub 2021 Jun 17.

12. Hu WY, Li XX, Diao YF, Qi JJ, Wang DL, Zhang JB, Sun BX, Liang S. Asiatic acid protects oocytes against in vitro aging-induced deterioration and improves subsequent embryonic development in pigs. Aging (Albany NY). 2020 Dec 3;13(3):3353-3367. doi: 10.18632/aging.202184. Epub 2020 Dec 3.

13. Zhang S, Guo J, Liang M, Qi J, Wang Z, Jian X, Zhang Z, Sun B, Li Z. miR-196a Promotes Proliferation and Inhibits Apoptosis of Immature Porcine Sertoli Cells. DNA Cell Biol. 2019 Jan;38(1):41-48. doi: 10.1089/dna.2018.4387. Epub 2018 Nov 14.

14. Guo J, Liu X, Yang Y, Liang M, Bai C, Zhao Z, Sun B. miR-375 down-regulation of the rearranged L-myc fusion and hypoxia-induced gene domain protein 1A genes and effects on Sertoli cell proliferation. Asian-Australas J Anim Sci. 2018 Aug;31(8):1103-1109. doi: 10.5713/ajas.17.0338. Epub 2018 Mar 2.

15. Guo J, Zhou M, Liu X, Pan Y, Yang R, Zhao Z, Sun B. Porcine IFI30 inhibits PRRSV proliferation and host cell apoptosis in vitro. Gene. 2018 Apr 5;649:93-98. doi: 10.1016/j.gene.2018.01.065. Epub 2018 Jan 31.

16. Yang Y, Fang X, Yang R, Yu H, Jiang P, Sun B, Zhao Z. MiR-152 Regulates Apoptosis and Triglyceride Production in MECs via Targeting ACAA2 and HSD17B12 Genes. Sci Rep. 2018 Jan 11;8(1):417. doi: 10.1038/s41598-017-18804-x.

17. C. Bai, Y. Pan, D. Wang, F. Cai, S. Yan, Z. Zhao and B. Sun. Genome-wide association analysis of residual feed intake in Junmu No. 1 White pigs. Animal Genetics, 2017,48, 686–690

18. Zhou M, Li C, Lu C, Zhang X, Pan Y, Liu X, Liu G, Zhao Z, Sun BX*. miRNA29 Promotes Viral Replication During Early Stage of PRRSV Infection In Vitro. DNA Cell Biol. Epub 2016 Sep 22. 2016 Oct;35(10):636-642.

19. Bai C, Li Y, Yan S, Fang H, Sun B, Zhang J, Zhao Z. Identification and characterization of the cDNA sequence encoding amelogenin in rabbit (Oryctolagus cuniculus).gene.2015.11.004. Epub 2015 Nov 6.Gene. 2016 Feb 1;576(2 Pt 2):770-5.

20. Xiaojun Zhanga,Chuangming Li, Chunyan Lu, Yonghong Zhang, Runjun Yang Zhihui Zhao, Boxing Sun*，Differential Expression of miR-499 and Validation of Predicted Target Genes in the Testicular Tissue of Swine at Different Developmental Stages，DNA and Cell Biology,vol34,7,2015

21. Xiaojun Zhang, Wei Zhao, Chuanmin Li, Zhihui Zhao, Boxing Sun*, Differential Expression of miR-34c and its Predicted Target Genes in Testicular Tissue at Different Development Stages of Swine, Asian Australas. J. Anim. Sci.vol28.No.11. 2015.